JobsCyber SecurityUnited StatesCybersecurity Engineer / Information System Security Engineer (ISSE) – DoD Healthcare

Leidos

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Cybersecurity Engineer / Information System Security Engineer (ISSE) – DoD Healthcare

Leidos · United States

Full-timeRemote5-10 yrs$87k–$157kListed as no visa sponsorshipDefense and Space Manufacturing
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In short

The Cybersecurity Engineer will support the security engineering, compliance, and continuous monitoring of enterprise healthcare technology solutions for the DoD. Responsibilities include developing authorization artifacts, maintaining system security documentation, and coordinating with government stakeholders to obtain and maintain an Authority to Operate (ATO).

What they're looking for

MUST-HAVE SKILLS

Risk Management Framework (RMF)ATO authorization documentationSystem Security Plans (SSP)NIST SP 800-53 controlsPOA&M managementCloud security principlesBachelor's degree in a technical field

ALSO MENTIONED

Salesforce Government Cloud PlusAWS GovCloudDoD IL4/IL5 environments

Candidates must have a bachelor's degree in a technical discipline with 4–8 years of relevant experience, or a master's degree with 2–6 years of experience. Required expertise includes DoD Risk Management Framework (RMF) processes, NIST SP 800-53 controls, and experience with cloud-based security architectures.

About the employer

Leidos

An industry & technology leader serving government & commercial customers with smarter, more efficient innovations

Leidos is an industry and technology leader serving government & commercial customers with smarter, more efficient digital and mission innovations. Headquartered in Reston, Virginia, with 47,000 global employees, Leidos reported annual revenues of approximately $17.2 billion for the fiscal year ended January 2, 2026.

Read more

Leidos was cited for the meaningful work employees perform that is challenging, impactful, and aligned with our customers’ missions as reasons professionals want to work and stay at our company. Leidos has also been named to lists including Forbes’ Best Employers for Diversity, Forbes’ America’s Best Employers for Women, Military Times Best for Vets Employers, and Ethisphere Institute’s World's Most Ethical Companies®. Employees enjoy career enrichment opportunities available through mobility and development and experience rewarding relationships with supportive supervisors and talented colleagues and customers. Employees appreciate our flexible work environment, allowing for and encouraging a true work-life balance. Our professionals are also excited about our Employee Resource Groups, like the Collaborative Outreach with Remote and Embedded Employees (CORE), which strives to create an environment where every employee, regardless of location, feels fully engaged as a valued employee of Leidos. Your most important work is ahead, visit careers.leidos.com for our latest opportunities.

INDUSTRY
Defense and Space Manufacturing
COMPANY
Public Company
FOUNDED
1969
HEADQUARTERS
Reston, Virginia
SIZE
10,001+on LinkedIn
OFFICES
12 on LinkedIn
OPEN HERE
26 roles

KNOWN FOR

DefenseIntelSensorsHealth SystemsEnterprise ITCyber

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Questions about this role

Is this Leidos role remote?
Tagged remote.
What does it pay?
The posting lists $87,100–$157,450 a year.
Does it sponsor visas?
Listed as no visa sponsorship.
What experience does it ask for?
Listed as 5-10 years.

The posting, in full

Leidos is seeking an experienced Cybersecurity Engineer / Information System Security Engineer (ISSE) to support the security engineering, system authorization, compliance, and continuous monitoring of enterprise healthcare technology solutions supporting the Department of Defense (DoD) and Defense Health Agency (DHA).

▶ READ THE FULL POSTING

Leidos is seeking an experienced Cybersecurity Engineer / Information System Security Engineer (ISSE) to support the security engineering, system authorization, compliance, and continuous monitoring of enterprise healthcare technology solutions supporting the Department of Defense (DoD) and Defense Health Agency (DHA).

The successful candidate will be responsible for developing and maintaining system security documentation, supporting implementation and validation of cybersecurity controls, preparing authorization artifacts, and coordinating activities required to obtain and maintain an Authority to Operate (ATO). The supported environment includes Salesforce Health Cloud, Amazon Connect, AWS GovCloud, identity and access management services, enterprise integrations, and associated cloud infrastructure.

This position will work closely with Leidos cybersecurity leadership, government security personnel, system administrators, developers, solution architects, and cloud engineers to ensure system development and operations comply with applicable DoD/DHA cybersecurity requirements throughout the system lifecycle.

Primary Responsibilities

  • Support cybersecurity engineering throughout system design, development, integration, deployment, and sustainment of Salesforce Health Cloud, Amazon Connect, and associated cloud services.
  • Develop, maintain, and coordinate required DoD/DHA ATO and Risk Management Framework (RMF) documentation, including System Security Plans (SSPs), security control implementation narratives, security boundary diagrams, data flow diagrams, and supporting authorization artifacts.
  • Prepare and maintain security control responsibility matrices, hardware/software inventories, ports and protocols documentation, interconnection agreements, and Plans of Action and Milestones (POA&Ms).
  • Coordinate with government Information System Security Managers (ISSMs), Information System Security Officers (ISSOs), security assessors, and Leidos cybersecurity personnel throughout the authorization process.
  • Review system architectures, integrations, cloud configurations, and application designs to identify cybersecurity requirements, risks, and potential compliance gaps.
  • Support implementation and validation of NIST SP 800-53 security controls, secure configuration baselines, access controls, encryption, logging, and monitoring capabilities.
  • Evaluate cloud service security requirements, inherited controls, shared responsibility models, and authorization boundaries for Salesforce, AWS, and associated services.
  • Coordinate vulnerability assessments, security scanning, configuration reviews, and remediation activities across system components.
  • Track cybersecurity findings, vulnerabilities, POA&Ms, and corrective actions through validation and closure.
  • Support continuous monitoring activities, including security control assessments, audit log reviews, vulnerability reporting, and compliance documentation.
  • Conduct security impact assessments for application enhancements, configuration changes, new integrations, and software releases.
  • Collaborate with developers and administrators to implement secure development practices and remediate application security vulnerabilities.
  • Support security incident investigation, response coordination, evidence collection, and corrective action activities in accordance with approved procedures.
  • Maintain accurate security documentation, authorization evidence, compliance records, and technical security procedures.
  • Communicate cybersecurity risks, authorization status, compliance findings, and remediation progress to program management and government stakeholders.

Required Qualifications

  • Bachelor's degree in Cybersecurity, Computer Science, Information Technology, Information Systems, Engineering, or a related technical discipline and 4–8 years of relevant experience, or a master's degree with 2–6 years of relevant experience. Equivalent experience may be considered in accordance with Leidos policies.
  • At least 3 years of experience in cybersecurity engineering, information assurance, system security engineering, or security assessment and authorization activities.
  • Demonstrated experience supporting DoD Risk Management Framework (RMF) processes and preparing or maintaining system authorization documentation.
  • Experience developing System Security Plans, security control implementation narratives, POA&Ms, and supporting ATO artifacts.
  • Working knowledge of NIST SP 800-53 security controls, DoD cybersecurity policies, and system authorization requirements.
  • Experience reviewing technical architectures, system configurations, data flows, and security control implementations.
  • Familiarity with cloud security principles, shared responsibility models, identity and access management, encryption, logging, and vulnerability management.
  • Experience reviewing vulnerability assessment results, tracking remediation activities, and supporting continuous security monitoring.
  • Strong analytical, problem-solving, technical documentation, communication, and collaboration skills.
  • Ability to independently manage cybersecurity engineering assignments and coordinate with developers, administrators, cybersecurity personnel, and government representatives.
  • Ability to meet applicable DoD/DHA personnel security and suitability requirements.
  • Ability to satisfy applicable DoD cybersecurity workforce qualification requirements for the assigned position.

Preferred Qualifications

  • Experience supporting ATO activities for DoD, DHA, VA, or other federal healthcare systems.
  • Experience preparing authorization packages for cloud-hosted or SaaS-based enterprise applications.
  • Familiarity with Salesforce Government Cloud Plus / Government Cloud Plus – Defense security architecture.
  • Experience with AWS GovCloud, Amazon Connect, AWS IAM, CloudTrail, CloudWatch, and associated AWS security capabilities.
  • Experience supporting DoD IL4/IL5 environments and understanding of the DoD Cloud Computing

Please be advised that during the interview, you will be required to keep your camera on, and your interviewer will be taking your picture for identification purposes if an offer letter is extended to you.

If you're looking for comfort, keep scrolling. At Leidos, we outthink, outbuild, and outpace the status quo — because the mission demands it. We're not hiring followers. We're recruiting the ones who disrupt, provoke, and refuse to fail. Step 10 is ancient history. We're already at step 30 — and moving faster than anyone else dares.

Original Posting

November 13, 2026

For U.S. Positions: While subject to change based on business needs, Leidos reasonably anticipates that this job requisition will remain open for at least 3 days with an anticipated close date of no earlier than 3 days after the original posting date as listed above.

Pay Range

Pay Range $87,100.00 - $157,450.00

The Leidos pay range for this job level is a general guideline only and not a guarantee of compensation or salary. Additional factors considered in extending an offer include (but are not limited to) responsibilities of the job, education, experience, knowledge, skills, and abilities, as well as internal equity, alignment with market data, applicable bargaining agreement (if any), or other law.

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This listing comes from Leidos's own careers site. Apply links go to the employer. Company facts are from Leidos's public profile. Last checked 14 Nov 2026.